منابع مشابه
Structural analogues antagonistic to thyroxine.
Since many compounds related structurally in specific ways to metabolically important substances have been found to produce signs of deficiency of the analogous metabolite, Woolley (1) proposed that’ new series of pharmacological agents might be produced by altering the structures of vitamins or hormones in definite ways. It was considered possible that such inhibitory structural analogues coul...
متن کاملStructural Analogues Antagonistic to Thyroxine
Since many compounds related structurally in specific ways to metabolically important substances have been found to produce signs of deficiency of the analogous metabolite, Woolley (1) proposed that’ new series of pharmacological agents might be produced by altering the structures of vitamins or hormones in definite ways. It was considered possible that such inhibitory structural analogues coul...
متن کاملEffects of triiodothyronine and other thyroxine analogues on thyroxine-binding in human serum.
The strong affinity between thyroxine and the specific thyroxine-binding protein (TBP) of human serum (1) is apparent from, a) the inability to remove more than small amounts of thyroxine from the serum by prolonged dialysis (2), and b) the effectiveness with which TBP competes with albumin for available thyroxine in serum, despite its much smaller concentration. Thyroxine bound to TBP is, neve...
متن کاملThe effect of thyroxine analogues on lipid an lipoprotein metabolism
Nutzungsbedingungen Die ETH-Bibliothek ist Anbieterin der digitalisierten Zeitschriften. Sie besitzt keine Urheberrechte an den Inhalten der Zeitschriften. Die Rechte liegen in der Regel bei den Herausgebern. Die auf der Plattform e-periodica veröffentlichten Dokumente stehen für nicht-kommerzielle Zwecke in Lehre und Forschung sowie für die private Nutzung frei zur Verfügung. Einzelne Dateien ...
متن کاملSYNTHESIS AKD BIOLOGICAL ACTIVITY OF SOME TRIIODINATED ANALOGUES OF THYROXINE* BY KEXKICHI TOMITAt
Although it has been clearly established that thyroxine is the main circulating form of the thyroid hormone (1, 2), there is some evidence in favor of the view that it must be converted to some other substance before it is fully effective in peripheral tissues. Among these points of evidence are (a) t.he lag period between thyroxine administration and a detectable response in basal metabolic ra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1962
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)84530-1